| Devil DinosaurVanguard | Nerf | Less base health. | 55.8% → 55.0% | -0.8 |
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| HulkVanguard | Buff | Faster Banner shots, more gamma from self-hits; stronger team-up with Wolverine. | 53.3% → 53.9% | +0.6 |
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| MagnetoVanguard | Buff | Team-up with Emma Frost hits harder and lasts longer. | 47.4% → 47.4% | +0.0 |
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| The ThingVanguard | Buff | Team-up with Invisible Woman comes back sooner and heals more easily. | 45.4% → 46.0% | +0.6 |
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| CyclopsDuelist | Buff | More Optic Blast damage, cheaper ultimate, longer team-up with Gambit. | 43.3% → 46.1% | +2.8 |
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| GorrDuelist | Nerf | Less scythe and shockwave damage and a shorter ultimate. | 57.2% → 55.6% | -1.6 |
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| HawkeyeDuelist | Buff | Faster arrows, quicker recovery, stronger team-ups with Psylocke and Cloak & Dagger. | 45.5% → 47.8% | +2.3 |
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| Iron ManDuelist | Rework | Missile barrage now tracks targets, with half the damage per missile. | 49.7% → 50.4% | +0.8 |
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| PhoenixDuelist | Rework | More damage; self-healing swapped for capped bonus health. | 42.4% → 49.4% | +7.0 |
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| Scarlet WitchDuelist | Nerf | Less damage from Chthonian Burst's spell field. | 52.5% → 50.2% | -2.4 |
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| Adam WarlockStrategist | Buff | More healing from the team-up with Ultron. | 51.2% → 51.1% | -0.1 |
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| GambitStrategist | Mixed | Faster card charges, but a shorter ultimate range and smaller jump boost. | 48.7% → 48.0% | -0.7 |
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| JubileeStrategist | Buff | New self-healing and more ultimate healing; shorter blind. | 49.3% → 50.2% | +0.9 |
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